GreenLight is dedicated to bringing our Cell-Free process for the production of RNA to market to address global needs and threats. The team at GreenLight is composed of world leaders in diverse fields all working towards one goal. A dynamic and fast-paced environment is cultivated with employees not only aligned with GreenLight's mission, but also passionate about the technology and science. We are always seeking passionate and talented people that are ready to lead the coming RNA revolution.

GreenLight is an equal opportunity employer. We pride ourselves on the diversity of our workforce. We believe in a culture of transparency, integrity, gender equality and inclusion.

Open Positions


Senior Engineer – Process development, Pilot Plant, Scale-up and Manufacturing

Position Summary:

GreenLight Biosciences is seeking an exceptional, highly-motivated scale-up and manufacturing engineer to scale up cell-free bioprocessing and manufacture products using our core technology. The successful candidate will integrate with process development team and manage people and resources to scale the bio-processes to pilot and commercial scale. Strong technical, organizational, management and communication skills, and ability to cope up with a fast-paced environment, are essential.

 

Responsibilities:

  • Review, evaluate, develop manufacturing processes with man, machine, material and methods considered.

  • Develop, evaluate, and review instructions, specifications and methods to support the product life cycle transitions from development into production.

  • Lead/Perform cell-culture and cell free production campaigns (pilot-commercial) scale to support process definition, product development, demonstration runs for multiple programs in the pipeline.

  • Prepares product and process reports by collecting, analyzing, and summarizing information and trends.

  • Provides manufacturing decision-making information to support capacity planning for labor, production schedules, and estimating future requirements.

  • Completes design and development projects by training and guiding manufacturing personnel.

  • Has a firm understanding of all equipment for which he/she is responsible to include set-up, adjustment and assessment of possible improvements.

 

Qualifications:

  • Ph.D. in chemical engineering, biological engineering, or equivalent.
  • 7+ years of work experience in industrial biotechnology, food or pharmaceutical industry in a pilot plant process development and/or manufacturing setting.
  • Must have hands on experience with bioreactors/fermenters and related unit operations (such as primary cell separation, filtration, HTST, and drying unit operations) in bench, pilot and commercial scale.
  • Must have proven experience in process planning and development (project management, capacity planning, floor layout, material flows, capabilities).
  • Proven record of equipment design & selection, development and validation.
  • Fundamental understanding of principles of biochemical engineering, material & energy balances, scale up and manufacturing is required.
  • Proven record of commercializing bioprocesses from early stage to production stage is desired.
  • Experience with technical transfer of materials and processes to customers and/or contract manufacturing facilities is a plus.
  • Must be able to read engineering drawings.
  • Must be familiar with continuous improvement philosophy and implementation: statistical tools, Lean principles, six sigma, etc.
  • Experience with ASPEN, or similar software is a plus.
  • History of progressive responsibility and people management is a plus.
  • Must be highly-motivated with exceptional communication, leadership, and teamwork skills.

Head of Fungicide Innovation

GreenLight Biosciences is seeking an exceptional, highly-motivated scientific leader to apply cutting edge RNA technology to Crop Protection. The Head of Fungicide Innovation reports to the Director of Crop Protection Discovery and will be responsible for defining and executing the technical research strategy to discover novel nucleic-acid based fungicides. Strong technical, organizational, and communication skills, as well as the ability to develop creative solutions to challenging problems in a fast-paced milestone-driven company are essential.

Qualities:

  • Results-oriented with a passion for developing cutting-edge technology
  • An ability to seamlessly combine hands-on work at the bench with building and managing a growing team 
  • A can-do attitude to drive success for all aspects of the project, team and company
  • If you are a visionary out-of-the box thinker that can help GreenLight unlock RNA-based solutions for crop protection and transform current agricultural practices, you may be the leader we seek.

Responsibilities:

  • Collaborate as a member of the Crop Protection Discovery Leadership Team to:
  • Develop a research strategy to discover novel biopesticides and ensure a robust product pipeline
  • Allocate resources and troubleshoot challenges across the Crop Protection Discovery organization to ensure achievement of key goals and milestones
  • Identify and evaluate new technologies for licensing or acquisition
  • Source and secure external collaborations 
  • Drive achievement of Fungicide Discovery goals to ensure a continual supply of early-stage products for advancement to development
  • Direct and actively participate in internal and third-party research projects required for novel fungicide discovery and demonstration of product proof-of-concept, including target selection, design of active RNAi molecules, in vitro and in vivo fungal assay development, and innovation of novel nucleic acid delivery mechanisms to fungal pathogens and their crop hosts
  • Serve as a subject matter expert in fungal biology, plant pathology and plant-pathogen interactions
  • Contribute to the company’s intellectual property portfolio and routinely track and document results in laboratory notebooks and databases
  • Mentor, coach, challenge and develop team members to reach their full potential
  • Ensure safe laboratory operations and a safety-focused work culture
  • As a scientific leader at GreenLight, role model, support and deliver on the corporate values, objectives and goals
  • Represent GreenLight at scientific meetings and conferences as required
  • Foster an inclusive work environment that embraces and derives value from diversity, teamwork and sharing


Requirements: 

  • A Ph.D. in plant pathology, mycology, plant biology or related field, ideally with substantial experience in the areas of RNAi and/or fungicide research
  • At least 5 years of relevant postdoctoral experience, preferably with at least 2 years in an industrial setting
  • Solid knowledge of the relevant academic research literature and crop protection industry, especially in fungicide discovery and RNA-based control of fungal diseases
  • A record of and interest in scientific leadership, with at least 1 year of experience managing a team
  • Experience effectively managing multiple projects with appropriate attention to detail and communication of project progress, deviations and results to stakeholders in a clear and timely fashion
  • Experience in the following areas provides a distinct advantage:
  • External research collaboration management
  • Building teams and establishing research programs
  • Discovery of new crop protection products through a commercial screening program
  • Use of genomics and bioinformatics tools
  • Successful grant writing

 

Scientist I/II – Nucleic Acid Biochemistry

Position Summary

GreenLight Biosciences is seeking an exceptional and highly motivated analytical scientist to help advance the company’s RNA platform technology. The successful candidate will support R&D efforts within the company by characterizing RNA products with respect to structure, sequence, and modifications. A deep technical background in analytical chemistry, molecular biology, and assay development is required. Strong organizational and communication skills, creative problem-solving, and flexibility are essential.

 Responsibilities:

  • Characterize the structure, sequence, and modifications of RNA molecules using state-of-the-art techniques, including HPLC, LC-MS/MS, capillary electrophoresis, next-generation sequencing, etc.
  • Purify RNA products using state-of-the art techniques, such as reverse-phase chromatography, ion exchange chromatography, size exclusion chromatography, solid-phase extraction, etc.
  • Evaluate purity of RNA samples for nucleic acid, protein, and other contaminants
  • Design and perform standard molecular biology experiments (DNA cloning, nuclease digestion, PCR, (q)RT-PCR, agarose gel electrophoresis, etc.)
  • Develop novel analytical methods where necessary
  • Work independently and in collaboration with multidisciplinary project teams, as well as the Analytical Chemistry and Metabolic Engineering groups
  • Maintain diligent and organized records
  • Clearly communicate results and recommendations to colleagues, managers, and senior management, assisting in project decision-making

 Qualifications:

  • Ph.D. in Biochemistry, Molecular Biology, or related discipline with at least 3 years of industrial experience or 5 years of academic experience, specializing in the RNA field. Candidates with a M.S. and at least 8 years of industrial experience in the RNA field will also be considered.
  • Experience characterizing nucleic acid modifications, including nucleoside and post-transcriptional modifications (e.g. 5’-cap structures, polyadenylation, etc.) is required
  • Experience characterizing primary and secondary structures of nucleic acids is required
  • Experience developing analytical chemistry methods (e.g. HPLC and LC-MS) is required
  • Experience with standard molecular biology techniques is required
  • Experience with next-generation approaches to RNA sequencing is desirable
  • Experience translating bench scale experiments to high throughput workflows is desirable
  • Strong organization, communication, and interpersonal skills are required, with the ability to work both independently and in a collaborative work environment

Scientist I/II – Strain Engineering

Position Summary

GreenLight Biosciences is seeking an exceptional and highly motivated microbial strain engineer to help advance the company’s RNA platform technology.  The successful candidate will support R&D efforts within the company by engineering microbial genomes and building DNA-based constructs to provide inputs to the company’s proprietary bioproduction technology.  A strong technical background in synthetic biology, microbial physiology and bioinformatics is required.  Strong organizational and communication skills, creative problem-solving, and flexibility are essential for thriving in this small start-up company with a fast-paced environment.

 Responsibilities:

  • Design, build, and optimize microbial strains employing standard molecular biology techniques such as PCR, DNA subcloning, agarose gel electrophoresis, DNA sequencing analysis, cell transformation, cell culture, and other more advanced methods in support of strain development projects
  • Execute & analyze small-scale experiments to test engineered strains prior to bench-scale fermentor trials
  • Collaborate with other Strain Engineering Team members to facilitate the successful achievement of project goals and milestones in a timely manner
  • Collaborate with the Fermentation Team for successful testing of new strains at bench-scale and beyond
  • Collaborate with the Pathway Engineering Team to deliver next-generation strains that advance GreenLight’s cell-free reaction technology
  • Work independently and as part of a team on multidisciplinary projects
  • Maintain diligent and organized records
  • Clearly communicate results and recommendations to colleagues, managers, and senior management, to assist in project decision-making

 Qualifications:

  • Ph.D. in Biochemistry, Chemical Engineering, Microbiology, or related discipline with at least 3 years of industrial experience or 5 years of academic experience, specializing in microbial strain engineering. Candidates with a M.S. and at least 8 years of industrial strain experience will also be considered.

  • Experience in working with Escherichia coli and Bacillus subtilis is required.  Familiarity with other microorganisms would be a plus.
  • Deep understanding of chromosomal editing of microbial genomes is required, including use of CRISPR/Cas9 technology.
  • Handling of next-generation DNA sequencing data using appropriate bioinformatics tools is desirable
  • Experience translating bench-scale experiments to high throughput workflows is desirable
  • Strong organization, communication, and interpersonal skills are required, with the ability to multitask in a fast-paced environment.

Scientist / Engineer – mRNA Downstream Processing

 

Position Summary

GreenLight Biosciences is seeking an exceptional and highly motivated scientist or engineer to help advance the company’s RNA platform technology. The successful candidate will support R&D efforts within the company by developing scalable processes to purify messenger RNA (mRNA). A deep technical background in chromatography, centrifugation, filtration and end-to-end purification process development is required. Strong organizational and communication skills, creative problem-solving, and flexibility are essential.

Responsibilities:
 

  • Develop scalable processes for purification of clinical-grade messenger RNA, using a wide variety of chromatography, filtration, and centrifugation methods.
  • Manage downstream production of mRNA in-house, liaising with downstream counterparts at partners where appropriate.
  • Utilize current analytical methods and develop novel analytical methods where necessary to monitor product quality.
  • Work independently and in collaboration with multidisciplinary project teams, as well as the Analytical Chemistry and Metabolic Engineering groups.
  • Maintain diligent and organized records.
  • Clearly communicate results and recommendations to colleagues, managers, and senior management, assisting in project decision-making.

Qualifications:

  • Ph.D. in Chemical Engineering, Chemistry, Biochemistry, or related discipline with at least 3 years of industrial experience or 5 years of academic experience, specializing in the mRNA field. Candidates with a M.S. and at least 8 years of industrial experience in the mRNA field will also be considered.
  • Experience with nucleic acid process development (e.g. mRNA, dsRNA, DNA) is required.
  • Experience developing processes involving complex biological mixtures is required.
  • Experience developing chromatographic separation processes (including ion exchange, affinity, reverse-phase, size exclusion, etc.) and filtration processes (including ultrafiltration, tangential flow filtration, diafiltration, etc.) is required.
  • Experience scaling up / scaling down separation processes is required.
  • Experience with liquid chromatography (HPLC, FPLC) is required.
  • Experience with enzymatic reactions is desirable.
  • Knowledge of statistical design of experiments (DOE) is desirable.
  • Experience with Good Manufacturing Practices (GMP) is desirable.
  • Strong organization, communication, and interpersonal skills are required, with the ability to work both independently and in a collaborative work environment

Scientist I / II – Pathway & Process Development

 

Position Summary:

GreenLight Biosciences is seeking an exceptional, highly-motivated metabolic or biochemical engineer to work on cutting edge cell-free bioprocessing technology. The successful candidate will support research on the discovery, engineering, and optimization of biochemical pathways & processes in the context of several milestone-driven projects. Strong technical, organizational, and communication skills, as well as the ability to develop creative solutions to challenging problems, are essential.

 

Responsibilities:

  • Design, execute & analyze experiments at different scales (ranging from microliters to tens of liters) for pathway & process testing, debottlenecking & optimization
  • Research biological pathways and associated enzymes for the production of target molecules
  • Perform molecular biology techniques such as PCR, DNA subcloning, in vitro transcription, cell transformation, cell culture, and other more advanced methods in support of research projects
  • Collaborate with the analytical team to identify & develop analytical methods to investigate the cell-free reaction system
  • Collaborate with the downstream processing team in developing processes for improved recovery of pathway enzymes & products of interest
  • Work collaboratively with other team members to accomplish project goals and milestones
  • Use creative problem-solving skills to independently troubleshoot experimental challenges
  • Analyze, summarize, and present experimental results to team members and management
  • Contribute to technical discussions related to the development and application of GreenLight’s proprietary bioproduction technology
  • Continuously contribute to the company’s intellectual property portfolio and routinely track and document results in laboratory notebooks and databases

 

Qualifications:

  • Ph.D. in chemical engineering, bioengineering, molecular biology, biochemistry, or equivalent
  • 0-3 years of experience in the biotechnology industry
  • Fundamental understanding of principles of biochemical engineering, material & energy balances & metabolic networks is required
  • Strong background in molecular biology, microbial physiology, and biochemical pathway engineering with expertise on cutting-edge technologies for pathway/organism manipulation
  • Experience in process development, statistical design of experiments & modeling is highly desired
  • Familiarity with techniques for metabolite, protein & nucleic acid isolation, detection & quantitation as well as development of enzyme assays is a major plus
  • Must be highly-motivated with exceptional communication, leadership, and teamwork skills

Sr. Research Associate – Pathway Engineering

 

Position Summary:

GreenLight Biosciences is seeking an exceptional, highly-motivated Research Associate / Sr. Research Associate to work on cutting edge cell-free bioprocessing technology. The successful candidate will support research on the discovery, engineering, and optimization of biochemical pathways & processes in the context of several milestone-driven projects. Strong technical, organizational, and communication skills, as well as the ability to develop creative solutions to challenging problems, are essential.

Responsibilities:

  • Execute & analyze experiments and associated analytics (such as enzyme assays) at different scales (ranging from 10s of µLs to 10s of Ls) for pathway & process testing, debottlenecking & optimization
  • Independently plan & perform routine molecular biology techniques such as PCR, DNA subcloning, in vitro transcription, cell transformation, cell culture, protein expression & purification and other more advanced methods in support of research projects
  • Maintain detailed records about experimental protocols and procedures followed in the form of lab notebooks
  • Work collaboratively with other team members to accomplish project goals and milestones
  • Use creative problem-solving skills to independently troubleshoot experimental challenges
  • Analyze, summarize, and present experimental results to team members and management
  • Must demonstrate skills in multitasking, organization, attention to detail, interpersonal, communication, judgement, planning and prioritizing, recognizing cause and effect
  • Maintain a clean, organized and safe work environment
  • Contribute to technical discussions related to the development and application of GreenLight’s proprietary bioproduction technology
  • Continuously contribute to the company’s intellectual property portfolio and routinely track and document results in laboratory notebooks and databases

Qualifications:

  • B.S. or M.S. in chemical engineering, bioengineering, molecular biology, biochemistry, or equivalent
  • Two or more years of experience in the biotechnology or pharmaceutical industry
  • Strong background in molecular biology and biochemistry with experience in recombinant DNA technologies, protein analysis, cell transformation, and cell culture including:
    • Proficiency in microbial culturing and aseptic techniques (required)
    • Basic understanding of microbial metabolism and nutritional requirements (desired)
    • Experience engineering metabolic pathways in microbial hosts is (desired)
  • Familiarity with analytical techniques for metabolite, protein & nucleic acid detection & quantitation is a major plus
  • Must be highly-motivated with exceptional communication, leadership, and teamwork skills

Research Associate (I/II/III/Senior) and/or Postdoctoral Engineer – Process Development

GreenLight Biosciences is seeking exceptional, highly-motivated Research Associate(s) to work on the process development of cutting edge fermentations and cell free bioprocessing technology. The successful candidate will be involved in high throughput screening of strains/cell free reactions, and/or process development of commercially relevant fermentations/cell free reactions in 10 mL to 150 L reactors. The successful candidate will work hands-on in small teams to execute fermentation/cell free bioprocessing and other associated bioprocess unit operations with a high degree of excellence, in a fast-paced environment. A high degree of flexibility, creativity and initiative is essential for success. Strong technical, organization, communication, documentation, inter-personal, and trouble shooting skills are essential. The RA will comply with company policies and practices for EHS and will support company and organizational targets and functional growth plans. 

 

RESPONSIBILITIES:

 

  • Operate and monitor fermentations/cell free reactions and conduct associated analytics (such as optical densities, dry cell weights, culture plating, protein analysis), in small teams at different scales (10 mL to 150 L) with limited supervision.
  • Analyze experimental data and generate data driven conclusions for process development and optimization.
  • Summarize experimental results and present to team members, other engineers and scientists in the company.
  • Maintain detailed records about experimental protocols and procedures followed in the form of lab notebooks.
  • Keeps an inventory of chemicals, raw materials, and other components produced.
  • Weighs and checks raw materials. Makes media, assembles, and cleans equipment and processes.
  • Adheres to good manufacturing practices and standard operating procedures.
  • Assists in the revision and creation of process documents, such as SOPs.
  • Must demonstrate skills in organization, attention-to-detail, interpersonal communication, judgement, planning and prioritization, recognizing cause and effect.
  • Establish and follow written procedures for the clear and accurate documentation of equipment operation, process instructions and process data.
  • Maintain a clean, organized and safe work environment.

 

QUALIFICATIONS:

 

  • A.S. or B.S. or M.S or Ph.D. in Chemical Engineering, Biological Engineering, Molecular Biology, Biochemistry or equivalent.
  • 0-5 years of experience in biotechnology/food/pharma industry.
  • Relevant undergraduate/graduate experience in an academic or industrial setting will be preferred.
  • Proficiency with microbial culture and aseptic techniques is required.
  • Strong technical competence in microbial metabolism, microbiology, molecular biology is required.
  • Familiarity and practical understanding of how to correctly operate basic laboratory equipment: including fermenters, DO probes, pH meters, mass spec, lab scales, centrifuges, shakers, sterile hoods, etc.
  • Personal track record and accomplishments in laboratory and executing experiments. Attention to detail and ownership of work is critical.
  • Ability to read and follow detailed instructions and record information accurately.
  • Ability to observe and react with unexpected experimental results.
  • Data-driven decision maker with knowledge and experience in data management tools.
  • Demonstrated ability to prioritize multiple tasks and demand on resources and accomplish goals.
  • Ability to read and follow detailed instructions and record information accurately.
  • Ability to observe and react with unexpected experimental results.
  • Data-driven decision maker with knowledge and experience in data management tools.
  • Demonstrated ability to prioritize multiple tasks and demand on resources and accomplish goals.
  • High quality standards for one’s own work is required.
  • Strong Analytical, Problem Solving, Planning and Organizational skills.
  • Ability to work independently and in teams to meet objectives and timelines.
  • Ability to lift 40 lbs.
  • Ability to work evening shifts.
  • Experience in high through-put reactors is a plus.
  • Familiarity with analytical techniques for metabolite, protein, and nucleic acid detection and quantification is a plus.
  • Must be flexible, approachable, highly motivated, with excellent communication and interpersonal skills.

 

EDUCATION:

Associate’s, Bachelor’s, Master’s or Doctoral degree in Microbiology, Biochemistry, Chemical Engineering, Biological Engineering or similar Life Sciences discipline required.


Research Associate – Analytical Chemistry

GreenLight Biosciences is seeking an exceptional, highly-motivated and collaborative Research Associate to join the Analytical Chemistry team and help develop our proprietary cell-free bioprocessing platform to enable the production of novel RNAi products for the agricultural industries. The successful candidate will work closely with a diverse R&D team to achieve overall company goals and develop the platform of cell-free bioprocessing. Strong technical, organizational, and interpersonal skills, along with a commitment to excellence and high-quality work are required.

Responsibilities:

  • Operate and maintain analytical instrumentation, including HPLC/UPLC, LC-MS, IC, and GC systems
  • Execute a range of established, HPLC-based assays to quantify target analytes in various sample matrices, following established SOPs
  • Execute a range of standardized, plate-based assays, using spectrophotometric of fluorometric plate readers for analyte detection
  • Process data, including some statistical analysis, calibration quality assessment, QC tracking, and deliver reports to multidisciplinary R&D team members
  • Be accountable for accuracy of data analysis and timely processing of samples
  • Detail-oriented tracking and documenting of experimental results and instrument performance in laboratory notebooks and company databases
  • Analyze, summarize, and present experimental results to manager and other team members
  • Work collaboratively with other R&D team members to accomplish project goals and milestones
  • Use creative problem-solving skills to troubleshoot experimental challenges
  • General laboratory assistance including lab equipment maintenance, preparation of reagents, and ordering/receiving of lab supplies
  • Stay up to date with scientific and technical development within the field of analytical chemistry

 Qualifications:

  • B.S. or M.S. in chemistry, biochemistry, or equivalent
  • 3+ years industry experience working in an analytical chemistry laboratory
  • Strong background in chemistry, with knowledge of biochemistry and microbial metabolism a plus
  • Experience with molecular biology protocols and biopolymers such as RNA is preferred
  • Familiarity with diverse analytical techniques for metabolite detection/quantification
  • Experience with Agilent Chemstation, Waters Empower, or similar chromatography data systems
  • Hands on experience troubleshooting analytical equipment
  • The successful candidate must have high quality standards for one’s own work, strong communication skills, and a commitment to team success

1. Your name and contact information

2. Firm information

3. Areas of specialization

Name *
Name
(Size, Location, What you provide)
(Industry, Roles)